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  • 產(chǎn)品名稱:PDHB 抗原(重組蛋白)

  • 產(chǎn)品型號:100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:800
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:


中文名稱: PDHB 抗原(重組蛋白)

英文名稱: PDHB Antigen (Recombinant Protein)

別     名:  pyruvate dehydrogenase E1 beta subunit; PDHBD; PHE1B; PDHE1B; PDHE1-B

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Fusion protein corresponding to a region derived from 31-359 amino acids of human PDHB

技術(shù)規(guī)格

Full name:

pyruvate dehydrogenase E1 beta subunit

Synonyms:

PDHBD; PHE1B; PDHE1B; PDHE1-B

Swissprot:

P11177

Gene Accession:

BC000439

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]





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