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  • 產品名稱:DOK1抗原(重組蛋白)

  • 產品型號:1mg
  • 產品廠商:通蔚生物
  • 產品價格:3580
  • 產品庫存:35
  • 產品文檔:
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詳情介紹:


中文名稱: DOK1抗原(重組蛋白)

英文名稱: DOK1 Antigen (Recombinant Protein)

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述 

Fusion protein corresponding to C terminal 300 amino acids of human DOK1

技術規(guī)格

Full name:

docking protein 1, 62kDa (downstream of tyrosine kinase 1)

Synonyms:

P62DOK

Swissprot:

Q99704

Gene Accession:

BC114440

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.





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