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  • 產(chǎn)品名稱：YPEL3抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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詳情介紹：

中文名稱： YPEL3抗原（重組蛋白）

英文名稱： YPEL3 Antigen (Recombinant Protein)

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

yippee like 3

Swissprot:

P61236

Gene Accession:

BC005009

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both ***** and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors. Involved in proliferation and apoptosis in myeloid precursor cells.





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