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  • 產(chǎn)品名稱：PCNA抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：


中文名稱： PCNA抗原（重組蛋白）

英文名稱： PCNA Antigen (Recombinant Protein)

儲(chǔ)     存：  冷凍（-20℃）
  
相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 8-256 amino acids of human PCNA

技術(shù)規(guī)格


Full name:

Proliferating cell nuclear antigen

Synonyms:

ATLD2

Swissprot:

P12004

Gene Accession:

BC000491

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome







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