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  • 產品名稱:KRT13抗原(重組蛋白)

  • 產品型號:1mg
  • 產品廠商:通蔚生物
  • 產品價格:3580
  • 產品庫存:35
  • 產品文檔:
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詳情介紹:

中文名稱: KRT13抗原(重組蛋白)

英文名稱:  KRT13 Antigen (Recombinant Protein)

儲     存:  冷凍(-20℃)

相關類別: 抗原

概     述

Fusion protein corresponding to a region derived from 274-412 amino acids of human KRT13

技術規(guī)格

Full name:

keratin 13

Synonyms:

K13; CK13

Swissprot:

P13646

Gene Accession:

BC077718

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.





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