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  • 產(chǎn)品名稱：CYP21A2抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：

中文名稱： CYP21A2抗原（重組蛋白）

英文名稱： CYP21A2 Antigen (Recombinant Protein)

別     名：  CAH1; CPS1; CA21H; CYP21; CYP21B; P450c21B

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

cytochrome P450, family 21, subfamily A, polypeptide 2

Synonyms:

CAH1; CPS1; CA21H; CYP21; CYP21B; P450c21B

Swissprot:

P08686

Gene Accession:

BC128535

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene.





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