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  • 產(chǎn)品名稱:ADD1 抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
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詳情介紹:

中文名稱: ADD1 抗原(重組蛋白)

英文名稱: ADD1 Antigen (Recombinant Protein)

別     名:  Alpha-adducin; ADDA

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

Alpha-adducin

Synonyms:

ADDA

Swissprot:

P35611

Gene Accession:

BC013393

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.





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