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  • 產(chǎn)品名稱：TLR5抗原（重組蛋白）

  • 產(chǎn)品型號：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：800
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：

中文名稱： TLR5抗原（重組蛋白）

英文名稱： TLR5 Antigen (Recombinant Protein)

別     名：  TIL3; SLEB1

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述：

Fusion protein corresponding to a region derived from 3-180 amino acids of human TLR5

技術規(guī)格

Full name:

toll-like receptor 5

Synonyms:

TIL3; SLEB1

Swissprot:

O60602

Gene Accession:

BC109119

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.





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