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  • 產(chǎn)品名稱(chēng)：TLR4抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：800
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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詳情介紹：

中文名稱(chēng)： TLR4抗原（重組蛋白）

英文名稱(chēng)： TLR4 Antigen (Recombinant Protein)

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類(lèi)別： 抗原
 
概     述：

Fusion protein corresponding to a region derived from 662-839 amino acids of human TLR4

技術(shù)規(guī)格

Full name:

toll like receptor 4

Synonyms:

TOLL; CD284; TLR-4; ARMD10

Swissprot:

O00206

Gene Accession:

BC117422

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.





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