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  • 產(chǎn)品名稱：SETD2抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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詳情介紹：

中文名稱： SETD2抗原（重組蛋白）


英文名稱： SETD2 Antigen (Recombinant Protein)

別     名：  HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概    述：

Fusion protein corresponding to C terminal 250 amino acids of human SETD2

技術(shù)規(guī)格


Full name:

SET domain containing 2

Synonyms:

HYPB; SET2; HIF-1; HIP-1; KMT3A; HBP231; HSPC069; p231HBP

Swissprot:

Q9BYW2

Gene Accession:

BC117162

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.





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