英文名稱: PPAT Antigen (Recombinant Protein)
Full name: |
phosphoribosyl pyrophosphate amidotransferase |
Synonyms: |
GPAT; PRAT; ATASE |
Swissprot: |
Q06203 |
Gene Accession: |
BC004200 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. |
