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  • 產(chǎn)品名稱：PLA2G4A抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：
中文名稱： PLA2G4A抗原（重組蛋白）

英文名稱： PLA2G4A Antigen (Recombinant Protein)

別     名：  PLA2G4; cPLA2-alpha

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述：

Fusion protein corresponding to N terminal 178 amino acids of human PLA2G4A

技術規(guī)格

Full name:

phospholipase A2, group IVA (cytosolic, calcium-dependent)

Synonyms:

PLA2G4; cPLA2-alpha

Swissprot:

P47712

Gene Accession:

BC114340

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.





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