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  • 產(chǎn)品名稱：FLT3抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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FLT3抗原（重組蛋白）公司秉承“專注品質(zhì)、信守承諾、積極溝通、chuang新服務(wù)”的企業(yè)文化積極參與生物領(lǐng)域的技術(shù)chuang新和技術(shù)服務(wù)，力求為我國科研事業(yè)添磚加瓦，嚴(yán)格的質(zhì)控體系，建立和完善企業(yè)制度，創(chuàng)造性發(fā)展，客戶的滿意就是我們的宗旨。
詳情介紹：
中文名稱： FLT3抗原（重組蛋白）

英文名稱： FLT3 Antigen (Recombinant Protein)

別     名：  FLK2; STK1; CD135; FLK-2

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to a region derived from 610-943 amino acids of human FLT3

技術(shù)規(guī)格

Full name:

fms related tyrosine kinase 3

Synonyms:

FLK2; STK1; CD135; FLK-2

Swissprot:

P36888

Gene Accession:

BC126350

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.







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