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  • 產(chǎn)品名稱：ELP2抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
ELP2抗原（重組蛋白）公司秉承“專注品質(zhì)、信守承諾、積極溝通、chuang新服務(wù)”的企業(yè)文化積極參與生物領(lǐng)域的技術(shù)chuang新和技術(shù)服務(wù)，力求為我國科研事業(yè)添磚加瓦，嚴(yán)格的質(zhì)控體系，建立和完善企業(yè)制度，創(chuàng)造性發(fā)展，客戶的滿意就是我們的宗旨。
詳情介紹：
中文名稱： ELP2抗原（重組蛋白）

英文名稱： ELP2 Antigen (Recombinant Protein)

別     名：  StIP; StIP1; SHINC-2; STATIP1

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to a region derived from C terminal 250 amino acids of human ELP2

技術(shù)規(guī)格

Full name:

elongator acetyltransferase complex subunit 2

Synonyms:

StIP; StIP1; SHINC-2; STATIP1

Swissprot:

Q6IA86

Gene Accession:

BC032553

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.





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