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  • 產(chǎn)品名稱：EDN3抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
EDN3抗原（重組蛋白）公司秉承“專注品質(zhì)、信守承諾、積極溝通、chuang新服務(wù)”的企業(yè)文化積極參與生物領(lǐng)域的技術(shù)chuang新和技術(shù)服務(wù)，力求為我國科研事業(yè)添磚加瓦，嚴(yán)格的質(zhì)控體系，建立和完善企業(yè)制度，創(chuàng)造性發(fā)展，客戶的滿意就是我們的宗旨。
詳情介紹：
中文名稱： EDN3抗原（重組蛋白）

英文名稱： EDN3 Antigen (Recombinant Protein)

別     名：  ET3; ET-3; WS4B; HSCR4; PPET3

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to a region derived from 118-238 amino acids of human EDN3

技術(shù)規(guī)格

Full name:

endothelin 3

Synonyms:

ET3; ET-3; WS4B; HSCR4; PPET3

Swissprot:

P14138

Gene Accession:

BC008876

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.





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