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  • 產(chǎn)品名稱：CARF 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：800
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
CARF 抗原（重組蛋白）名稱免費(fèi)技術(shù)支持，由專業(yè)的技術(shù)人員和銷售人員，科研用戶提供**的技術(shù)支持和完善的售前、售中、售后服務(wù)。免費(fèi)代測(cè)、貨源充足、種屬齊全，滿足于生物、化學(xué)等領(lǐng)域定性、定量等研究實(shí)驗(yàn)。敬請(qǐng)來(lái)電咨詢！
詳情介紹：
中文名稱： CARF 抗原（重組蛋白）

英文名稱： CARF Antigen (Recombinant Protein)

別     名：  calcium responsive transcription factor; ALS2CR8; NYD-SP24

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to C terminal 300 amino acids of human CARF
    
技術(shù)規(guī)格

Full name:

calcium responsive transcription factor

Synonyms:

ALS2CR8; NYD-SP24

Swissprot:

Q8N187

Gene Accession:

BC033777

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

CARF (calcium-response factor), also known as ALS2CR8 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) or NYD-SP24, is a 725 amino acid nuclear protein. Expressed in a wide variety of tissues with highest expression in the hippocampus, CARF is thought to be a transcription factor that associates with the p53 tumor suppression pathway. CARF cooperates, co-localizes and is co-regulated with ARF, an ADP-ribosylation factor, and, through this interaction, helps to mediate ARF-p53-induced apoptotic signaling. This apoptotic pathway is implicated in cell cycle control, proper cellular development, response to DNA damage and the aging process, suggesting that CARF participates in various events throughout the cell.





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