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  • 產品名稱：AXIN2抗原（重組蛋白）

  • 產品型號：1mg
  • 產品廠商：通蔚生物
  • 產品價格：3580
  • 產品庫存：35
  • 產品文檔：
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簡單介紹：
AXIN2抗原（重組蛋白）自成立以來，就注重企業(yè)信息化的建設，主要用于科研實驗使用，采用了先進的內部供應鏈信息處理平臺，保證客戶訂單的準確、高效處理，客戶關系的管理系統(tǒng)和客戶關系管理團隊，能時間響應客戶的售前、售后需求。
詳情介紹：
中文名稱： AXIN2抗原（重組蛋白）

英文名稱： AXIN2 Antigen (Recombinant Protein)

別     名：  AXIL; ODCRCS

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述：

Fusion protein corresponding to N terminal 160 amino acids of human AXIN2

技術規(guī)格

Full name:

axin 2

Synonyms:

AXIL; ODCRCS

Swissprot:

Q9Y2T1

Gene Accession:

NP_004646

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.





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