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  • 產(chǎn)品名稱：ASCC1抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
ASCC1抗原（重組蛋白）自成立以來，就注重企業(yè)信息化的建設，主要用于科研實驗使用，采用了先進的內(nèi)部供應鏈信息處理平臺，保證客戶訂單的準確、高效處理，客戶關系的管理系統(tǒng)和客戶關系管理團隊，能時間響應客戶的售前、售后需求。
詳情介紹：
中文名稱： ASCC1抗原（重組蛋白）

英文名稱： ASCC1 Antigen (Recombinant Protein)

別     名：  p50; CGI-18; ASC1p50

儲     存：  冷凍（-20℃）

相關類別： 抗原
  
概     述：

Fusion protein corresponding to C terminal 250 amino acids of human ASCC1

技術規(guī)格

Full name:

activating signal cointegrator 1 complex subunit 1

Synonyms:

p50; CGI-18; ASC1p50

Swissprot:

Q8N9N2

Gene Accession:

BC012291

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.





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