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  • 產(chǎn)品名稱:APEH 抗原(重組蛋白)

  • 產(chǎn)品型號:100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:800
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:

中文名稱: APEH 抗原(重組蛋白)

英文名稱: APEH Antigen (Recombinant Protein)

別     名:  acylaminoacyl-peptide hydrolase; APH; OPH; AARE; ACPH; D3S48E; D3F15S2; DNF15S2

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述:

Fusion protein corresponding to a region derived from 433-732 amino acids of human APEH
    
技術(shù)規(guī)

Full name:

acylaminoacyl-peptide hydrolase

Synonyms:

APH; OPH; AARE; ACPH; D3S48E; D3F15S2; DNF15S2

Swissprot:

P13798

Gene Accession:

BC000362

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.





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