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  • 產(chǎn)品名稱:ADAM15 抗原(重組蛋白)

  • 產(chǎn)品型號(hào):100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:800
  • 產(chǎn)品庫存:35
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詳情介紹:
中文名稱: ADAM15 抗原(重組蛋白)

英文名稱: ADAM15 Antigen (Recombinant Protein)

別     名:  ADAM metallopeptidase domain 15; MDC15

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述:

Fusion protein corresponding to a region derived from 213-414 amino acids of human ADAM15
    
技術(shù)規(guī)格

Full name:

ADAM metallopeptidase domain 15

Synonyms:

MDC15

Swissprot:

Q13444

Gene Accession:

BC014566

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.







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