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  • 產品名稱：ACY1 抗原（重組蛋白）

  • 產品型號：100ug
  • 產品廠商：通蔚生物
  • 產品價格：800
  • 產品庫存：35
  • 產品文檔：
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ACY1 抗原（重組蛋白）公司是一家專業(yè)從事生物科研項目的企業(yè)，經銷優(yōu)異化生物試劑，國內外知名品牌ELISA試劑盒，標準品|對照品，抗體，培養(yǎng)基，血清的科研生物產品，竭誠為您提供行內*全、*新的產品信息。歡迎來電咨詢！
詳情介紹：
中文名稱： ACY1 抗原（重組蛋白）

英文名稱： ACY1 Antigen (Recombinant Protein)

別     名：  aminoacylase 1; ACY-1; ACY1D

儲     存：  冷凍（-20℃）

相關類別： 抗原
  
概     述：

Fusion protein corresponding to C terminal 250 amino acids of human ACY1
    
技術規(guī)格

Full name:

aminoacylase 1

Synonyms:

ACY-1; ACY1D

Swissprot:

Q03154

Gene Accession:

BC000545

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.





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