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  • 產(chǎn)品名稱：ACVR1抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
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詳情介紹：
中文名稱： ACVR1抗原（重組蛋白）

英文名稱： ACVR1 Antigen (Recombinant Protein)

別     名： FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2

儲     存： 冷凍（-20℃）

相關類別：抗原

概     述：

Fusion protein corresponding to a region derived from 260-509 amino acids of human ACVR1

技術規(guī)格

Full name:

activin A receptor type I

Synonyms:

FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2

Swissprot:

Q04771

Gene Accession:

BC033867

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.






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