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  • 產(chǎn)品名稱：AADACL2 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：800
  • 產(chǎn)品庫(kù)存：35
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詳情介紹：
中文名稱： AADACL2 抗原（重組蛋白）

英文名稱： AADACL2 Antigen (Recombinant Protein)

別     名：  arylacetamide deacetylase-like 2

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to C terminal 222 amino acids of human AADACL2
    
技術(shù)規(guī)格：

Full name:

arylacetamide deacetylase-like 2

Swissprot:

Q6P093

Gene Accession:

BC065724

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556–560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear.561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.





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