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  • 產(chǎn)品名稱：AADAC 抗原（重組蛋白）

  • 產(chǎn)品型號：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：800
  • 產(chǎn)品庫存：35
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詳情介紹：
中文名稱： AADAC 抗原（重組蛋白）

英文名稱： AADAC Antigen (Recombinant Protein)

別     名：  Arylacetamide deacetylase; DAC; CES5A1

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to C terminal 250 amino acids of human AADAC
    
技術(shù)規(guī)格：

Full name:

Arylacetamide deacetylase

Synonyms:

DAC; CES5A1

Swissprot:

P22760

Gene Accession:

BC032309

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.





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