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  • 產(chǎn)品名稱：VRK1 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
VRK1 抗原（重組蛋白）奉行以人為本、唯才善用，提倡人是核心資本，公平合理并創(chuàng)造性地使用人才，盡可能的給員工提供足夠的舞臺去發(fā)揮去成長，公司尊重人，尊重每一位員工的個性，依托這樣的人才觀，將進(jìn)一步完善科學(xué)合理的人力資源管理機(jī)制，造就一個良好的人才成長空間。
詳情介紹：
中文名稱： VRK1 抗原（重組蛋白）

英文名稱： VRK1 Antigen (Recombinant Protein)

別     名：  vaccinia related kinase 1; PCH1; PCH1A

相關(guān)類別： 抗原

儲     存：  冷凍（-20℃）

概     述

Fusion protein corresponding to a region derived from 197-396 amino acids of human VRK1

技術(shù)規(guī)格

Full name:

vaccinia related kinase 1

Synonyms:

PCH1; PCH1A

Swissprot:

Q99986

Gene Accession:

BC113510

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.





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