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  • 產(chǎn)品名稱：TMEM256 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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TMEM256 抗原（重組蛋白）以強大的專業(yè)背景、上等的客戶服務(wù)、完備的產(chǎn)品供應(yīng)和深厚的人脈資源，在同行業(yè)中保持良好的企業(yè)形象和競爭優(yōu)勢，在市場競爭日益激烈的今天，將始終堅持信譽立業(yè)、以人為本、質(zhì)量**、誠信服務(wù)的宗旨，不斷拼搏，開拓進取，與各界朋友攜手共創(chuàng)美好未來。
詳情介紹：

中文名稱： TMEM256 抗原（重組蛋白）

英文名稱： TMEM256 Antigen (Recombinant Protein)

別     名：  transmembrane protein 256; C17orf61

儲     存：  冷凍（-20℃）     

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 30-113 amino acids of human TMEM256

技術(shù)規(guī)格

Full name:

transmembrane protein 256

Synonyms:

C17orf61

Swissprot:

Q8N2U0

Gene Accession:

BC030270

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

TMEM256, also known as C17orf61, C17orf61 (chromosome 17 open reading frame 61) is a 113 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.





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