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  • 產(chǎn)品名稱：TG 抗原

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：350
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：



中文名稱： TG 抗原 

英文名稱： TG Antigen

相關(guān)類別： 抗原

儲     存：  冷凍（-20℃）  

概     述

Synthetic peptide corresponding to a region derived from 2754-2768 amino acids of human thyroglobulin

技術(shù)規(guī)格

Full name

thyroglobulin

Synonyms

TGN; AITD3

Swissprot

P01266

Gene Accession

NP_003226

Background

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.







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