產(chǎn)品中心
產(chǎn)品詳情

  • 產(chǎn)品名稱：兔抗THOC5多克隆抗體

  • 產(chǎn)品型號(hào)：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：1560
  • 產(chǎn)品庫(kù)存：60
  • 產(chǎn)品文檔：
你添加了1件商品 查看購(gòu)物車(chē)
簡(jiǎn)單介紹：
我司兔抗THOC5多克隆抗體9折起 ，為您提供專(zhuān)業(yè)的售前售后技術(shù)指導(dǎo)，我司始終堅(jiān)信：用心做好品質(zhì)，企業(yè)方能遠(yuǎn)航的理念，竭誠(chéng)為您服務(wù)。我們公司在您收到產(chǎn)品后有質(zhì)量問(wèn)題免費(fèi)包換的（除人為外），合同上注明清晰的，我們都會(huì)一律更換！
詳情介紹：

中文名稱：  兔抗THOC5多克隆抗體   

英文名稱： Anti-THOC5 rabbit polyclonal antibody

別      名： Fmip; PK1.3; fSAP79; C22orf19

相關(guān)類(lèi)別： 一抗

儲(chǔ)      存： 冷凍（-20℃） 避光

宿      主： Rabbit

抗      原： THOC5

反應(yīng)種屬： Human

標(biāo) 記 物： Unconjugate

克隆類(lèi)型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC5 in conjunction with ALYREF/THOC4 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in transcription elongation and genome stability. Involved in alternative polyadenylation site choice by recruiting CPSF6 to 5' region of target genes; probaly mediates association of the TREX and CFIm complexes. Regulates the expression of myeloid transcription factors CEBPA, CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate. May be involved in the differentiation of granulocytes and adipocytes. Essential for hematopoietic primitive cell survival and plays an integral role in monocytic development.

Applications:

WB, IHC

Name of antibody:

THOC5

Immunogen:

Synthesized peptide derived from internal of human THOC5.

Full name:

THO complex 5

Synonyms：

Fmip; PK1.3; fSAP79; C22orf19

SwissProt:

Q13769

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

79 kDa

WB Positive control:

Jurkat cells and HepG2 cells lysates

WB Recommended dilution:

500-3000





姓名：
電話：
您的需求：