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Background:
The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.
Applications:
ELISA, IHC
Name of antibody:
RHOBTB2
Immunogen:
Synthetic peptide of human RHOBTB2
Full name:
Rho-related BTB domain containing 2
Synonyms:
DBC2
SwissProt:
Q9BYZ6
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human thyroid cancer and Human gastric cancer
IHC Recommend dilution:
25-100