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Background:
C10orf28 (chromosome 10 open reading frame 28), also known as GIDRP88 (growth inhibition and differentiation-related protein 88) or putative mitochondrial space protein 32.1, is a 792 amino acid protein that exists as three alternatively spliced isoforms. The gene encoding C10orf28 maps to human chromosome 10, which spans nearly 135 million base pairs, makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Applications:
ELISA, IHC
Name of antibody:
R3HCC1L
Immunogen:
Synthetic peptide of human R3HCC1L
Full name:
R3H domain and coiled-coil containing 1-like
Synonyms:
PSORT; GIDRP86; GIDRP88; C10orf28
SwissProt:
Q7Z5L2
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human thyroid cancer and Human gastric cancer
IHC Recommend dilution:
50-200