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  • 產(chǎn)品名稱：NR1I3 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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簡(jiǎn)單介紹：
NR1I3 抗原（重組蛋白）科研研究已進(jìn)入全新時(shí)代，愛好生物研究的學(xué)者越來越多。不管你是花幾百還是上千，甚至上萬去購(gòu)置試劑，這都是*簡(jiǎn)單的**步。你之后需要付出更多的是大量的時(shí)間和精力，再加上你的耐心和用心，才能把這條路走的更遠(yuǎn)。
詳情介紹：

中文名稱： NR1I3 抗原（重組蛋白）

英文名稱： NR1I3 Antigen (Recombinant Protein)

別     名：  nuclear receptor subfamily 1 group I member 3; CAR; CAR1; MB67

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 153-352 amino acids of human NR1I3

技術(shù)規(guī)格

Full name:

nuclear receptor subfamily 1 group I member 3

Synonyms:

CAR; CAR1; MB67

Swissprot:

Q14994

Gene Accession:

BC069626

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.





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