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  • 產(chǎn)品名稱(chēng)：COX7A2L抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
  • 產(chǎn)品文檔：
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中文名稱(chēng)： COX7A2L抗原（重組蛋白）

英文名稱(chēng)： COX7A2L Antigen (Recombinant Protein)

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

cytochrome c oxidase subunit 7A2 like

Synonyms:

EB1; SIG81; COX7AR; COX7RP

Swissprot:

O14548

Gene Accession:

BC007095

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.






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