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  • 產(chǎn)品名稱:RICTOR抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:3580
  • 產(chǎn)品庫存:35
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詳情介紹:



中文名稱: RICTOR抗原(重組蛋白)

英文名稱: RICTOR Antigen (Recombinant Protein)

別     名:  PIA; AVO3; hAVO3
 
儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述:

Fusion protein corresponding to N terminal 257 amino acids of human RICTOR

技術(shù)規(guī)格

Full name:

RPTOR independent companion of MTOR, complex 2

Synonyms:

PIA; AVO3; hAVO3

Swissprot:

Q6R327

Gene Accession:

BC029608

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Rapamycin-insensitive companion of mTOR is a protein that in humans is encoded by the RICTOR gene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.







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