英文名稱: GFAP Antigen (Recombinant Protein)
相關(guān)類別: 抗原
概 述:
Full name: |
glial fibrillary acidic protein |
Synonyms: |
ALXDRD |
Swissprot: |
P14136 |
Gene Accession: |
BC013596 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
