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  • 產(chǎn)品名稱：DYNLL1抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：
中文名稱： DYNLL1抗原（重組蛋白）

英文名稱： DYNLL1 Antigen (Recombinant Protein)

別     名：  LC8; PIN; DLC1; DLC8; LC8a; DNCL1; hdlc1; DNCLC1

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to a region derived from 1-89 amino acids of human DYNLL1

技術(shù)規(guī)格

Full name:

dynein, light chain, LC8-type 1

Synonyms:

LC8; PIN; DLC1; DLC8; LC8a; DNCL1; hdlc1; DNCLC1

Swissprot:

P63167

Gene Accession:

NP_003737

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.






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