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  • 產(chǎn)品名稱:DCTN4抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:
中文名稱: DCTN4抗原(重組蛋白)

英文名稱: DCTN4 Antigen (Recombinant Protein)

別     名:  P62; DYN4

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述:

Fusion protein corresponding to C terminal 250 amino acids of human DCTN4

技術(shù)規(guī)格

Full name:

dynactin 4 (p62)

Synonyms:

P62; DYN4

Swissprot:

Q9UJW0

Gene Accession:

BC026323

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.





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