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  • 產(chǎn)品名稱:CERK抗原(重組蛋白)

  • 產(chǎn)品型號(hào):1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:3580
  • 產(chǎn)品庫(kù)存:35
  • 產(chǎn)品文檔:
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詳情介紹:
中文名稱: CERK抗原(重組蛋白)

英文名稱: CERK Antigen (Recombinant Protein)

別     名:  LK4; hCERK; dA59H18.2; dA59H18.3

儲(chǔ)
     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概     述:

Fusion protein corresponding to a region derived from 128-278 amino acids of human CERK

技術(shù)規(guī)格

Full name:

ceramide kinase

Synonyms:

LK4; hCERK; dA59H18.2; dA59H18.3

Swissprot:

Q8TCT0

Gene Accession:

BC126940

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.





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