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  • 產(chǎn)品名稱：BAP1抗原（重組蛋白）

  • 產(chǎn)品型號：100 ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：800
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
BAP1抗原（重組蛋白）自成立以來，就注重企業(yè)信息化的建設(shè)，主要用于科研實(shí)驗(yàn)使用，采用了先進(jìn)的內(nèi)部供應(yīng)鏈信息處理平臺，保證客戶訂單的準(zhǔn)確、高效處理，客戶關(guān)系的管理系統(tǒng)和客戶關(guān)系管理團(tuán)隊(duì)，能時(shí)間響應(yīng)客戶的售前、售后需求。
詳情介紹：
中文名稱： BAP1抗原（重組蛋白）

英文名稱： BAP1 Antigen (Recombinant Protein)

別     名：  UCHL2; hucep-6; HUCEP-13

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述：

Fusion protein corresponding to a region derived from 366-596 amino acids of human BAP1

技術(shù)規(guī)格

Full name:

BRCA1 associated protein 1

Synonyms:

UCHL2; hucep-6; HUCEP-13

Swissprot:

Q92560

Gene Accession:

BC001596

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.





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