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  • 產(chǎn)品名稱(chēng)：ACLY抗原（重組蛋白）

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詳情介紹：
中文名稱(chēng)： ACLY抗原（重組蛋白）

英文名稱(chēng)： ACLY Antigen (Recombinant Protein)

別     名：  ACL; ATPCL; CLATP

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類(lèi)別： 抗原

概     述：

Fusion protein corresponding to C terminal 250 amino acids of human ACLY

技術(shù)規(guī)格：

Full name:

ATP citrate lyase

Synonyms:

ACL; ATPCL; CLATP

Swissprot:

P53396

Gene Accession:

BC006195

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.





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