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  • 產(chǎn)品名稱：兔抗TJP1多克隆抗體

  • 產(chǎn)品型號：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：1560
  • 產(chǎn)品庫存：60
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詳情介紹：

中文名稱：兔抗TJP1多克隆抗體 

英文名稱： Anti-TJP1 rabbit polyclonal antibody

別      名： tight junction protein 1; ZO-1

相關(guān)類別： 一抗

儲      存： 冷凍（-20℃）

宿      主： Rabbit

抗      原： TJP1

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

TJP1

Immunogen:

Synthetic peptide of human TJP1

Full name:

tight junction protein 1

Synonyms:

ZO-1

SwissProt:

Q07157

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

30-150


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