中文名稱:兔抗SAV1多克隆抗體
英文名稱: Anti-SAV1 rabbit polyclonal antibody
別 名: salvador family WW domain containing protein 1; SAV; WW45; WWP4
相關類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: SAV1
反應種屬: Human, Mouse, Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規(guī)格
Background: |
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in ***** tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SAV1 |
Immunogen: |
Fusion protein of human SAV1 |
Full name: |
salvador family WW domain containing protein 1 |
Synonyms: |
SAV; WW45; WWP4 |
SwissProt: |
Q9H4B6 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human brain and Human gastric cancer |
IHC Recommend dilution: |
100-300 |
WB Predicted band size: |
45 kDa |
WB Positive control: |
HUVEC, PC-3 cell lysates |
WB Recommended dilution: |
500-2000 |